THE ADDICTION LIABILITY OF SYNTHETIC SUBSTITUTES FOR CODEINE -- (PROJECT DESCRIPTION) -- REQUEST TO THE OFFICE OF NAVAL RESEARCH FOR RENEWAL OF CONTRACT NR 101-149 WITH ATTACHMENT

Pan'%1 less so than codeine. Two promising potent analgesics, %IP 3-Hydroxp-N-phenethy1 benzmorphan (Nili-7519), and 3-Hydroxy-N- phenacy1morphinan (111H-7525), were partly investigated. Although both drugs are many times as potent as"morphine, abstinence was quite mild after withdrawal following direct addiction experiments...